HitPredict

Interactor 1: PSIP1 (O75475)
PC4 and SFRS1-interacting protein (CLL-associated antigen KW-7) (Dense fine speckles 70 kDa protein) (DFS 70) (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52)
Gene: PSIP1

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.928

Property	Details
Experiments	26912663, 29568061, 34079125, 9865721, 27154821
Identification Methods	unspecified method, pull down, proximity labelling technology, affinity chromatography technology, x-ray crystallography
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Hs			1 136
+	Hs
		265993 PSIP1_HUMAN (1-530): 1.2e-79: 260: 100.00		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		935205 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		1086307 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		952607 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		1157224 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		H3C_HUMAN (1-136): 5.49e-58: 177: 93.38
+	Hs
		935129 NSD1_HUMAN (2-529): 5.98e-69: 243: 11.41		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		1086280 NSD1_HUMAN (2-529): 5.98e-69: 243: 11.41		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		952555 NSD1_HUMAN (2-529): 5.98e-69: 243: 11.41		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		265969 PSIP1_HUMAN (1-530): 1.2e-79: 260: 100.00		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		828367 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		331780 NSD2_HUMAN (3-444): 2.88e-58: 211: 13.09		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		855452 MSH6_HUMAN (4-317): 4.4e-58: 211: 15.64		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		331823 NSD2_HUMAN (3-444): 2.88e-58: 211: 13.09		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		331787 NSD2_HUMAN (3-444): 2.88e-58: 211: 13.09		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		855454 MSH6_HUMAN (4-317): 4.4e-58: 211: 15.64		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		331833 NSD2_HUMAN (3-444): 2.88e-58: 211: 13.09		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Hs
		111558 MSH6_HUMAN (4-317): 4.4e-58: 211: 15.64		K7EK07_HUMAN (1-132): 2.4e-59: 181: 96.21
+	Hs
		828350 NSD1_HUMAN (2-529): 5.98e-69: 243: 11.41		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		331748 NSD2_HUMAN (3-444): 2.88e-58: 211: 13.09		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		828177 MSH6_HUMAN (4-317): 4.4e-58: 211: 15.64		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00