HitPredict

Interactor 1: PSIP1 (O75475)
PC4 and SFRS1-interacting protein (CLL-associated antigen KW-7) (Dense fine speckles 70 kDa protein) (DFS 70) (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52)
Gene: PSIP1

Interactor 2: H33 (P84243)
Histone H3.3
Gene: H3-3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36089195
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Hs			1 136
+	Hs
		265990 PSIP1_HUMAN (1-530): 1.2e-79: 260: 100.00		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		935205 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		952607 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		1086307 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		H31T_HUMAN (1-136): 2.58e-59: 181: 93.38
+	Hs
		1157224 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		H3C_HUMAN (1-136): 1.99e-56: 173: 95.59
+	Hs
		935129 NSD1_HUMAN (2-529): 5.98e-69: 243: 11.41		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		952555 NSD1_HUMAN (2-529): 5.98e-69: 243: 11.41		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		1086280 NSD1_HUMAN (2-529): 5.98e-69: 243: 11.41		H31T_HUMAN (1-136): 2.58e-59: 181: 93.38
+	Hs
		265969 PSIP1_HUMAN (1-530): 1.2e-79: 260: 100.00		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76
+	Hs
		828367 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76
+	Hs
		331780 NSD2_HUMAN (3-444): 2.88e-58: 211: 13.09		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		855452 MSH6_HUMAN (4-317): 4.4e-58: 211: 15.64		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		331787 NSD2_HUMAN (3-444): 2.88e-58: 211: 13.09		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		855454 MSH6_HUMAN (4-317): 4.4e-58: 211: 15.64		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		331823 NSD2_HUMAN (3-444): 2.88e-58: 211: 13.09		H31T_HUMAN (1-136): 2.58e-59: 181: 93.38
+	Hs
		331833 NSD2_HUMAN (3-444): 2.88e-58: 211: 13.09		H32_HUMAN (1-136): 5.32e-59: 180: 97.06
+	Hs
		828350 NSD1_HUMAN (2-529): 5.98e-69: 243: 11.41		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76
+	Hs
		111558 MSH6_HUMAN (4-317): 4.4e-58: 211: 15.64		K7EK07_HUMAN (1-132): 7.81e-58: 177: 100.00
+	Hs
		331748 NSD2_HUMAN (3-444): 2.88e-58: 211: 13.09		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76
+	Hs
		828177 MSH6_HUMAN (4-317): 4.4e-58: 211: 15.64		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76