HitPredict

Interactor 1: PSIP1 (O75475)
PC4 and SFRS1-interacting protein (CLL-associated antigen KW-7) (Dense fine speckles 70 kDa protein) (DFS 70) (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52)
Gene: PSIP1

Interactor 2: TF7L2 (Q9NQB0)
Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (hTCF-4)
Gene: TCF7L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	30833792
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 619
+	Hs
		265968 PSIP1_HUMAN (1-530): 1.2e-79: 260: 100.00		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		818361 NSD1_HUMAN (2-529): 5.98e-69: 243: 11.41		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		331678 NSD2_HUMAN (3-444): 2.88e-58: 211: 13.09		NSD2_HUMAN (251-564): 1.22e-30: 130: 13.97
+	Hs
		989547 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		SOX4_HUMAN (349-420): 8.6e-16: 82.5: 33.33
+	Mm
		818678 MSH6_MOUSE (4-317): 7.34e-61: 219: 14.68		SOX2_MOUSE (318-613): 2.17e-26: 111: 14.15
+	Hs
		855461 MSH6_HUMAN (4-317): 4.4e-58: 211: 15.64		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Mm
		818754 GLYR1_MOUSE (4-205): 1.09e-36: 144: 20.98		SOX2_MOUSE (318-613): 2.17e-26: 111: 14.15
+	Hs
		818107 GLYR1_HUMAN (4-215): 5.73e-35: 139: 20.27		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		331751 HDGF_HUMAN (3-225): 5.03e-24: 102: 38.94		NSD2_HUMAN (251-564): 1.22e-30: 130: 13.97
+	Hs
		1300993 ZMYD8_HUMAN (10-490): 5.97e-17: 86.4: 13.32		CIC_HUMAN (43-578): 1.85e-33: 139: 15.01
+	Hs
		850912 HDGF_HUMAN (3-225): 5.03e-24: 102: 38.94		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Hs
		996736 HDGR2_HUMAN (1-521): 2.98e-21: 99.5: 20.73		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Hs
		996954 ZMYD8_HUMAN (10-490): 5.97e-17: 86.4: 13.32		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Hs
		1246354 THOC2_HUMAN (106-366): 2.25e-09: 62.4: 14.59		CIC_HUMAN (43-578): 1.85e-33: 139: 15.01
+	Hs
		1342352 ZMYD8_HUMAN (10-490): 5.97e-17: 86.4: 13.32		HM20A_HUMAN (250-461): 2.79e-27: 115: 14.15
+	Hs
		818600 ZMYD8_HUMAN (10-490): 5.97e-17: 86.4: 13.32		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69