HitPredict

Interactor 1: TAD2A (O75478)
Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein)
Gene: TADA2A

Interactor 2: GCR (P04150)
Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
Gene: NR3C1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	9649342
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 443 Hs			1 777
+	Hs
		377556 SMRC1_HUMAN (63-373): 1.11e-34: 139: 11.90		GCR_HUMAN (1-777): 0: 933: 100.00
+	Hs
		261370 NCOR1_HUMAN (66-377): 8.47e-16: 82.3: 11.15		GCR_HUMAN (1-777): 0: 933: 100.00
+	Hs
		266321 TAD2A_HUMAN (1-443): 1.37e-170: 487: 100.00		HNF4A_HUMAN (397-757): 7.17e-101: 321: 23.42
+	Hs
		369916 TAD2B_HUMAN (13-442): 1.41e-114: 344: 26.68		ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06
+	Hs
		1198564 TAD2B_HUMAN (13-442): 1.41e-114: 344: 26.68		ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34
+	Hs
		487561 TAD2B_HUMAN (13-442): 1.41e-114: 344: 26.68		ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15
+	Hs
		782586 TAD2B_HUMAN (13-442): 1.41e-114: 344: 26.68		HNF4A_HUMAN (397-757): 7.17e-101: 321: 23.42
+	Mm
		956817 SMRC1_MOUSE (63-373): 6.16e-37: 146: 12.15		ERR2_MOUSE (316-761): 1.69e-113: 352: 24.44
+	Xl
		546248 Q1W3Z6_XENLA (46-379): 9.65e-47: 175: 11.21		THAA_XENLA (372-760): 3.05e-100: 317: 21.80
+	Hs
		261369 NCOR1_HUMAN (66-377): 8.47e-16: 82.3: 11.15		ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06
+	Hs
		487644 SMRC1_HUMAN (63-373): 1.11e-34: 139: 11.90		ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15
+	Hs
		611482 SMRC1_HUMAN (63-373): 1.11e-34: 139: 11.90		NR4A1_HUMAN (268-762): 5.59e-103: 331: 20.88
+	Hs
		782616 SMRC1_HUMAN (63-373): 1.11e-34: 139: 11.90		HNF4A_HUMAN (397-757): 7.17e-101: 321: 23.42
+	Hs
		261372 NCOR1_HUMAN (66-377): 8.47e-16: 82.3: 11.15		PRGR_HUMAN (232-777): 2.39e-110: 359: 40.00
+	Dm
		1211974 TAD2B_DROME (13-396): 1.9e-93: 294: 25.31		Q8WS79_DROME (419-662): 6.82e-30: 126: 31.83
+	Hs
		261381 NCOR1_HUMAN (66-377): 8.47e-16: 82.3: 11.15		RARA_HUMAN (316-759): 1.61e-105: 333: 19.60
+	Hs
		261380 NCOR1_HUMAN (66-377): 8.47e-16: 82.3: 11.15		ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15
+	Hs
		261390 NCOR1_HUMAN (66-377): 8.47e-16: 82.3: 11.15		RARG_HUMAN (317-776): 1.33e-100: 320: 18.48
+	Hs
		261382 NCOR1_HUMAN (66-377): 8.47e-16: 82.3: 11.15		THA_HUMAN (385-733): 1.19e-95: 308: 20.79
+	Hs
		1272965 SMRC1_HUMAN (63-373): 1.11e-34: 139: 11.90		NR2E1_HUMAN (402-676): 5.93e-25: 109: 25.83