HitPredict

Interactor 1: TAD2A (O75478)
Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein)
Gene: TADA2A

Interactor 2: KAT2B (Q92831)
Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) (Spermidine acetyltransferase KAT2B) (EC 2.3.1.57)
Gene: KAT2B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.940

The method score is based on:

Property Details
Experiments 24981860, 33961781, 37682711, 9885574, 9674425, 10373431
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Acetyltransf_1~Myb_DNA-binding
Common GO terms GO:0000124 - SAGA complex
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 9 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 443
Hs

1 832
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ At
+ Sc
+ At
+ Sc
+ Sc
+ At
+ At
+ At
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024