HitPredict

Interactor 1: TAD2A (O75478)
Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein)
Gene: TADA2A

Interactor 2: IKZF5 (Q9H5V7)
Zinc finger protein Pegasus (Ikaros family zinc finger protein 5)
Gene: IKZF5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0008270 - zinc ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 419
+	Hs
		1033693 SMRC1_HUMAN (63-373): 1.11e-34: 139: 11.90		IKZF1_HUMAN (2-419): 1.43e-117: 354: 21.19
+	Hs
		1272961 SMRC1_HUMAN (63-373): 1.11e-34: 139: 11.90		IKZF3_HUMAN (69-417): 3.02e-114: 345: 24.22
+	Hs
		1033769 NCOR2_HUMAN (71-375): 1.07e-09: 63: 9.54		IKZF1_HUMAN (2-419): 1.43e-117: 354: 21.19
+	Hs
		261492 NCOR1_HUMAN (66-377): 8.47e-16: 82.3: 11.15		REST_HUMAN (83-172): 5.62e-09: 60.5: 34.44
+	Hs
		1025046 SMRC2_HUMAN (124-364): 2.72e-11: 68.1: 10.16		REST_HUMAN (83-172): 5.62e-09: 60.5: 34.44