HitPredict

Interactor 1: SUPT3 (O75486)
Transcription initiation protein SPT3 homolog (SPT3-like protein)
Gene: SUPT3H

Interactor 2: UBP22 (Q9UPT9)
Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22)
Gene: USP22

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

The method score is based on:

Property	Details
Experiments	18838386, 24981860, 18206972, 35271311, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000124 - SAGA complex GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006282 - regulation of DNA repair and 4 others more... GO:0006357 - regulation of transcription by RNA polymerase II GO:0033276 - transcription factor TFTC complex GO:0043484 - regulation of RNA splicing GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	317
Hs

1	525

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024