HitPredict

Interactor 1: SUPT3 (O75486)
Transcription initiation protein SPT3 homolog (SPT3-like protein)
Gene: SUPT3H

Interactor 2: TAF6L (Q9Y6J9)
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) (PCAF-associated factor 65-alpha) (PAF65-alpha)
Gene: TAF6L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

The method score is based on:

Property	Details
Experiments	28514442, 33961781, 24981860, 11564863, 37682711
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000124 - SAGA complex GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005669 - transcription factor TFIID complex and 7 others more... GO:0006282 - regulation of DNA repair GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0043484 - regulation of RNA splicing GO:0045893 - positive regulation of DNA-templated transcription GO:0046982 - protein heterodimerization activity GO:0051123 - RNA polymerase II preinitiation complex assembly
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	317
Hs

1	622

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024