HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: RECQ4 (O94761)
ATP-dependent DNA helicase Q4 (EC 5.6.2.4) (DNA 3'-5' helicase RecQ4) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)
Gene: RECQL4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29229926
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 1208
+	Hs
		295405 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		RECQ4_HUMAN (1-1208): 0: 794: 100.00
+	Hs
		294714 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		RECQ4_HUMAN (1-1208): 0: 794: 100.00
+	Hs
		294794 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		RECQ4_HUMAN (1-1208): 0: 794: 100.00
+	Hs
		294308 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		RECQ4_HUMAN (1-1208): 0: 794: 100.00
+	Hs
		134252 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85
+	Hs
		134018 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85
+	Hs
		1271695 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50
+	Hs
		133858 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85
+	Hs
		571634 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		DDX5_HUMAN (374-903): 1.45e-115: 374: 16.18
+	Mm
		936480 TIAR_MOUSE (12-108): 8.8e-20: 89.6: 25.77		DDX5_MOUSE (374-903): 3.05e-115: 374: 16.18
+	Sc
		376580 PABP_YEAST (2-98): 4.25e-20: 91: 24.74		DED1_YEAST (410-849): 9.08e-110: 359: 16.06