HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 648
+	Hs
		374067 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374171 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		373604 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374066 TIAR_HUMAN (5-151): 6.76e-17: 81: 13.91		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		488705 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		488548 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		1217969 SRS12_HUMAN (1-251): 1.31e-38: 137: 46.33		KSR1_HUMAN (138-648): 6.15e-108: 348: 24.61
+	Hs
		266891 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		FYN_HUMAN (337-607): 2.33e-103: 326: 34.55
+	Hs
		522960 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		SRC_HUMAN (331-607): 3.01e-106: 333: 33.45
+	Hs
		516342 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		SRC_HUMAN (331-607): 3.01e-106: 333: 33.45
+	Hs
		523147 PABP3_HUMAN (2-99): 1.17e-17: 84: 18.37		SRC_HUMAN (331-607): 3.01e-106: 333: 33.45