HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: SRS11 (Q05519)
Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11)
Gene: SRSF11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 484
+	Hs
		984105 SRS12_HUMAN (1-251): 1.31e-38: 137: 46.33		SRS11_HUMAN (1-484): 6.69e-53: 187: 100.00
+	Hs
		984135 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		SRS11_HUMAN (1-484): 6.69e-53: 187: 100.00
+	Hs
		963968 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		SRS11_HUMAN (1-484): 6.69e-53: 187: 100.00
+	Hs
		1246388 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		THOC2_HUMAN (224-482): 1.34e-35: 143: 22.66
+	Hs
		951949 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71
+	Hs
		1031405 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		TITIN_HUMAN (33-483): 2.57e-10: 65.4: 8.99
+	Hs
		516609 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		TITIN_HUMAN (33-483): 2.57e-10: 65.4: 8.99
+	Hs
		965152 PABP3_HUMAN (2-99): 1.17e-17: 84: 18.37		ANK2_HUMAN (209-479): 7.77e-09: 60.7: 19.57