HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: PABP5 (Q96DU9)
Polyadenylate-binding protein 5 (PABP-5) (Poly(A)-binding protein 5)
Gene: PABPC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 382
+	Hs
		516635 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		PABP5_HUMAN (1-382): 2.22e-103: 311: 100.00
+	Hs
		1119141 PAP1L_HUMAN (6-99): 1.67e-18: 86.3: 21.28		PABP5_HUMAN (1-382): 2.22e-103: 311: 100.00
+	Zm
		8143 A0A1D6ELH4_MAIZE (8-98): 2.4e-17: 83.2: 29.67		A0A1D6ELH4_MAIZE (108-381): 1.16e-57: 200: 31.05
+	Mm
		857332 SRSF2_MOUSE (4-90): 1.89e-24: 99.3: 45.65		TIA1_MOUSE (194-379): 5.58e-49: 171: 23.40
+	Mm
		665745 PABP1_MOUSE (2-99): 6.34e-19: 87.9: 17.35		TIA1_MOUSE (194-379): 5.58e-49: 171: 23.40
+	Hs
		474017 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		PAB4L_HUMAN (198-380): 1.64e-41: 151: 26.63
+	Hs
		474021 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		PAB4L_HUMAN (198-380): 1.64e-41: 151: 26.63
+	Hs
		516689 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		PABP3_HUMAN (19-201): 3.02e-32: 129: 28.64
+	Hs
		266904 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		PABP1_HUMAN (292-378): 3.47e-17: 85.1: 23.60
+	Sc
		376562 PABP_YEAST (2-98): 4.25e-20: 91: 24.74		PABP_YEAST (1-198): 1.85e-28: 118: 22.79
+	Hs
		582561 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		NUCL_HUMAN (4-96): 1.1e-19: 92.8: 30.11
+	Hs
		516744 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		PABP1_HUMAN (292-378): 3.47e-17: 85.1: 23.60
+	Hs
		582224 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		NUCL_HUMAN (4-96): 1.1e-19: 92.8: 30.11
+	Hs
		582231 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		NUCL_HUMAN (4-96): 1.1e-19: 92.8: 30.11
+	Hs
		516466 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		PABP1_HUMAN (292-378): 3.47e-17: 85.1: 23.60
+	Hs
		516355 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		NUCL_HUMAN (4-96): 1.1e-19: 92.8: 30.11
+	Hs
		516495 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		PABP1_HUMAN (292-378): 3.47e-17: 85.1: 23.60
+	Hs
		516339 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		PABP1_HUMAN (292-378): 3.47e-17: 85.1: 23.60