HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30209976
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~zf-CCCH
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 1191
+	Hs
		952132 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		964061 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1031467 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		516698 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1329984 PABP3_HUMAN (2-99): 1.17e-17: 84: 18.37		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		267006 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		951995 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		964003 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1031360 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		516550 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1136287 PABP3_HUMAN (2-99): 1.17e-17: 84: 18.37		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		516595 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		KMT2C_HUMAN (351-895): 4.49e-14: 79.7: 9.35
+	Hs
		963553 TIAR_HUMAN (5-151): 6.76e-17: 81: 13.91		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77