HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 2752
+	Hs
		1357564 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		952179 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		516749 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		952089 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		516546 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Hs
		1031405 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		516609 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		820908 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		516406 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		820889 TIAR_HUMAN (5-151): 6.76e-17: 81: 13.91		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		516766 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11
+	Hs
		516595 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		KMT2C_HUMAN (1760-2747): 2.06e-09: 65.9: 9.01
+	Hs
		965152 PABP3_HUMAN (2-99): 1.17e-17: 84: 18.37		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23