HitPredict

Interactor 1: GEMI (O75496)
Geminin
Gene: GMNN

Interactor 2: HXC9 (P31274)
Homeobox protein Hox-C9 (Homeobox protein Hox-3B)
Gene: HOXC9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	22615398
Identification Methods	nuclear magnetic resonance, pull down, isothermal titration calorimetry
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0017053 - transcription repressor complex GO:0045786 - negative regulation of cell cycle
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 209 Hs			1 260
+	Mm
		291757 GEMI_MOUSE (1-208): 9.69e-96: 278: 77.89		HXC9_MOUSE (1-241): 3.11e-56: 182: 99.59
+	Mm
		291760 GEMI_MOUSE (1-208): 9.69e-96: 278: 77.89		HXA10_MOUSE (30-258): 9.82e-40: 143: 37.82
+	Hs
		267126 GEMI_HUMAN (1-209): 1.39e-98: 286: 100.00		HXD10_HUMAN (60-258): 1.47e-32: 123: 35.58
+	Mm
		291758 GEMI_MOUSE (1-208): 9.69e-96: 278: 77.89		HXD10_MOUSE (60-258): 2.94e-32: 122: 35.10
+	Mm
		291761 GEMI_MOUSE (1-208): 9.69e-96: 278: 77.89		HXA11_MOUSE (3-256): 2.12e-30: 117: 23.68
+	Mm
		291756 GEMI_MOUSE (1-208): 9.69e-96: 278: 77.89		HXC8_MOUSE (45-257): 1.64e-30: 115: 27.10
+	Mm
		291754 GEMI_MOUSE (1-208): 9.69e-96: 278: 77.89		HXA7_MOUSE (85-257): 1.38e-29: 112: 29.48
+	Mm
		291755 GEMI_MOUSE (1-208): 9.69e-96: 278: 77.89		HXB7_MOUSE (71-252): 1.41e-29: 112: 30.81