HitPredict

Interactor 1: ECI2 (O75521)
Enoyl-CoA delta isomerase 2 (EC 5.3.3.8) (DRS-1) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Diazepam-binding inhibitor-related protein 1) (DBI-related protein 1) (Dodecenoyl-CoA isomerase) (Hepatocellular carcinoma-associated antigen 88) (Peroxisomal 3,2-trans-enoyl-CoA isomerase) (pECI) (Renal carcinoma antigen NY-REN-1)
Gene: ECI2

Interactor 2: AUHM (Q13825)
Methylglutaconyl-CoA hydratase, mitochondrial (3-MG-CoA hydratase) (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding protein/enoyl-CoA hydratase) (Itaconyl-CoA hydratase) (EC 4.2.1.56)
Gene: AUH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ECH_1~ECH_1
Common GO terms	GO:0005739 - mitochondrion GO:0006635 - fatty acid beta-oxidation
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 394 Hs			1 339
+	Hs
		267401 ECI2_HUMAN (1-394): 3.05e-158: 452: 100.00		ECH1_HUMAN (32-332): 2.09e-84: 259: 27.16
+	Hs
		267351 ECI2_HUMAN (1-394): 3.05e-158: 452: 100.00		ECI2_HUMAN (80-333): 2.06e-77: 244: 18.61
+	Hs
		671445 ECHM_HUMAN (116-392): 7.54e-95: 287: 20.50		AUHM_HUMAN (1-339): 5.05e-118: 345: 100.00
+	Hs
		1022489 ECH1_HUMAN (109-391): 5.01e-83: 258: 21.21		AUHM_HUMAN (1-339): 5.05e-118: 345: 100.00
+	Hs
		1045795 ECHD2_HUMAN (121-393): 2.24e-82: 255: 20.79		AUHM_HUMAN (1-339): 5.05e-118: 345: 100.00
+	Hs
		671402 ECHM_HUMAN (116-392): 7.54e-95: 287: 20.50		ECHM_HUMAN (40-339): 1.34e-101: 302: 29.67
+	Hs
		1045752 AUHM_HUMAN (143-393): 1.85e-65: 213: 19.07		AUHM_HUMAN (1-339): 5.05e-118: 345: 100.00
+	Hs
		1376994 CDYL_HUMAN (94-391): 1.83e-81: 262: 33.22		CDYL_HUMAN (5-332): 1.32e-79: 255: 20.18
+	Hs
		1376996 CDYL_HUMAN (94-391): 1.83e-81: 262: 33.22		CDY2_HUMAN (57-332): 1.14e-75: 244: 19.50
+	Hs
		73201 ECHD2_HUMAN (121-393): 2.24e-82: 255: 20.79		B4DYI6_HUMAN (1-223): 4.51e-70: 220: 97.76
+	Ec
		940135 PAAF_ECOLI (140-393): 1.04e-81: 252: 26.67		PAAG_ECOLI (76-339): 7.23e-67: 212: 30.97
+	Dm
		1376686 Q9W5W8_DROME (121-393): 8.7e-71: 226: 20.42		Q9W5W8_DROME (39-338): 1.84e-72: 228: 21.34
+	Ec
		466664 MENB_ECOLI (136-393): 7.83e-68: 217: 25.67		MENB_ECOLI (83-338): 3.02e-75: 234: 28.08
+	Hs
		778139 AUHM_HUMAN (143-393): 1.85e-65: 213: 19.07		ECHA_HUMAN (71-317): 7.9e-61: 209: 28.97
+	Dm
		1361727 Q9VG69_DROME (100-389): 1.63e-68: 222: 18.37		Q9VB17_DROME (82-276): 7.18e-20: 90.5: 30.61