HitPredict

Interactor 1: TADA3 (O75528)
Transcriptional adapter 3 (ADA3 homolog) (hADA3) (STAF54) (Transcriptional adapter 3-like) (ADA3-like protein)
Gene: TADA3

Interactor 2: RARA (P10276)
Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)
Gene: RARA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.636

Property	Details
Experiments	12235159, 20413580
Identification Methods	affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0019904 - protein domain specific binding GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 432 Hs			1 462
+	Hs
		267618 TADA3_HUMAN (1-432): 0: 523: 100.00		RXRA_HUMAN (1-420): 1.48e-129: 384: 30.16
+	Hs
		267626 TADA3_HUMAN (1-432): 0: 523: 100.00		RXRB_HUMAN (36-419): 1.41e-123: 371: 29.61
+	Hs
		267607 TADA3_HUMAN (1-432): 0: 523: 100.00		ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81
+	Hs
		267630 TADA3_HUMAN (1-432): 0: 523: 100.00		PPARG_HUMAN (66-416): 9.52e-115: 348: 30.26
+	Hs
		267674 TADA3_HUMAN (1-432): 0: 523: 100.00		ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89