HitPredict

Interactor 1: TAF5L (O75529)
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (TAF5L) (PCAF-associated factor 65 beta) (PAF65-beta)
Gene: TAF5L

Interactor 2: T22D1 (Q15714)
TSC22 domain family protein 1 (Cerebral protein 2) (HUCEP-2) (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein)
Gene: TSC22D1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0006366 - transcription by RNA polymerase II
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 589 Hs			1 1073
+	Dm
		51528 TAF5_DROME (4-581): 1.78e-109: 345: 29.27		A1Z6M0_DROME (192-991): 3.85e-21: 102: 14.55
+	Hs
		1281391 FBXW7_HUMAN (299-588): 2.98e-69: 239: 23.02		PRR36_HUMAN (9-1025): 1.05e-28: 127: 10.13
+	Hs
		1281504 FBXW7_HUMAN (299-588): 2.98e-69: 239: 23.02		T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15
+	Hs
		152678 FBXW7_HUMAN (299-588): 2.98e-69: 239: 23.02		KMT2D_HUMAN (25-798): 6.74e-09: 62.7: 13.60
+	Hs
		1318191 TBL1R_HUMAN (148-415): 4.12e-42: 160: 13.89		T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15
+	Hs
		245651 TBL1X_HUMAN (148-415): 5.11e-40: 155: 14.24		T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15
+	Hs
		577699 NLE1_HUMAN (417-588): 2.76e-49: 179: 30.34		SON_HUMAN (486-849): 3.79e-10: 66.5: 16.71
+	Hs
		152663 WDR5B_HUMAN (92-411): 4.19e-34: 134: 12.20		KMT2D_HUMAN (25-798): 6.74e-09: 62.7: 13.60
+	Dm
		1363032 Q9VCN9_DROME (464-586): 7.96e-24: 108: 21.14		Q9VLS7_DROME (1-689): 2.91e-10: 67: 9.43
+	Dm
		1370283 Q9VT91_DROME (419-586): 4.45e-16: 84: 17.86		Q9VLS7_DROME (1-689): 2.91e-10: 67: 9.43
+	Hs
		903374 WDR5_HUMAN (498-588): 8.41e-16: 80.9: 20.88		KMT2C_HUMAN (475-1071): 1.01e-09: 65.4: 8.46
+	Mm
		903669 WDR5_MOUSE (498-588): 8.41e-16: 80.9: 20.88		KMT2C_MOUSE (291-1072): 3.73e-09: 63.5: 9.47
+	Hs
		152622 WDR5_HUMAN (498-588): 8.41e-16: 80.9: 20.88		KMT2D_HUMAN (25-798): 6.74e-09: 62.7: 13.60
+	Hs
		903405 WDR5_HUMAN (498-588): 8.41e-16: 80.9: 20.88		CBP_HUMAN (362-900): 7.28e-09: 62.4: 12.04
+	Hs
		577684 SNR40_HUMAN (162-294): 1.95e-10: 64.7: 7.86		SON_HUMAN (486-849): 3.79e-10: 66.5: 16.71
+	Hs
		1153497 SNR40_HUMAN (162-294): 1.95e-10: 64.7: 7.86		ADNP2_HUMAN (653-1067): 2.23e-09: 63.7: 13.00