HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	27705803
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 Hs			1 531
+	Mm
		945926 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		TCPH_MOUSE (2-530): 0: 582: 27.75
+	Hs
		268244 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		TCPH_HUMAN (2-530): 0: 576: 27.93
+	Mm
		945984 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		TCPZ_MOUSE (1-531): 0: 574: 96.80
+	Hs
		267951 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		TCPG_HUMAN (3-528): 0: 559: 27.96
+	Mm
		946000 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		TCPG_MOUSE (3-528): 0: 558: 28.14
+	Mm
		945971 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		TCPE_MOUSE (3-528): 0: 542: 30.84
+	Hs
		1240450 POC1A_HUMAN (177-440): 1.72e-50: 177: 14.29		TCPH_HUMAN (2-530): 0: 576: 27.93
+	Hs
		770932 POC1A_HUMAN (177-440): 1.72e-50: 177: 14.29		TCPZ_HUMAN (1-531): 0: 573: 100.00
+	Hs
		826772 POC1A_HUMAN (177-440): 1.72e-50: 177: 14.29		TCPG_HUMAN (3-528): 0: 559: 27.96
+	Hs
		826784 POC1B_HUMAN (186-440): 4.25e-48: 173: 15.56		TCPG_HUMAN (3-528): 0: 559: 27.96
+	Hs
		821316 POC1A_HUMAN (177-440): 1.72e-50: 177: 14.29		TCPE_HUMAN (3-528): 0: 548: 30.47
+	Hs
		821326 POC1B_HUMAN (186-440): 4.25e-48: 173: 15.56		TCPE_HUMAN (3-528): 0: 548: 30.47
+	Hs
		770968 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		TCPZ_HUMAN (1-531): 0: 573: 100.00
+	Hs
		826807 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		TCPG_HUMAN (3-528): 0: 559: 27.96
+	Hs
		1202777 WDR5B_HUMAN (279-439): 2.9e-21: 96.1: 12.27		TCPH_HUMAN (2-530): 0: 576: 27.93
+	Hs
		770974 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		TCPZ_HUMAN (1-531): 0: 573: 100.00
+	Hs
		770916 WDR5B_HUMAN (279-439): 2.9e-21: 96.1: 12.27		TCPZ_HUMAN (1-531): 0: 573: 100.00
+	Hs
		826748 WDR5B_HUMAN (279-439): 2.9e-21: 96.1: 12.27		TCPG_HUMAN (3-528): 0: 559: 27.96
+	Hs
		821355 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		TCPE_HUMAN (3-528): 0: 548: 30.47
+	Hs
		1202774 WDR5B_HUMAN (279-439): 2.9e-21: 96.1: 12.27		TCPW_HUMAN (1-530): 0: 542: 85.85