HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	27705803, 30021884
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 Hs			1 545
+	Mm
		946000 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		TCPG_MOUSE (1-545): 0: 637: 97.25
+	Mm
		516950 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		TCPA_MOUSE (10-542): 0: 613: 32.91
+	Mm
		945926 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		TCPH_MOUSE (2-540): 0: 587: 31.50
+	Hs
		268244 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		TCPH_HUMAN (2-536): 0: 574: 31.18
+	Mm
		945971 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		TCPE_MOUSE (4-530): 0: 555: 31.96
+	Hs
		826772 POC1A_HUMAN (177-440): 1.72e-50: 177: 14.29		TCPG_HUMAN (1-545): 0: 640: 100.00
+	Hs
		826784 POC1B_HUMAN (186-440): 4.25e-48: 173: 15.56		TCPG_HUMAN (1-545): 0: 640: 100.00
+	Hs
		826807 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		TCPG_HUMAN (1-545): 0: 640: 100.00
+	Hs
		1240450 POC1A_HUMAN (177-440): 1.72e-50: 177: 14.29		TCPH_HUMAN (2-536): 0: 574: 31.18
+	Hs
		821316 POC1A_HUMAN (177-440): 1.72e-50: 177: 14.29		TCPE_HUMAN (4-530): 0: 559: 32.52
+	Hs
		821326 POC1B_HUMAN (186-440): 4.25e-48: 173: 15.56		TCPE_HUMAN (4-530): 0: 559: 32.52
+	Hs
		573371 POC1A_HUMAN (177-440): 1.72e-50: 177: 14.29		TCPA_HUMAN (10-533): 0: 549: 33.09
+	Hs
		573384 POC1B_HUMAN (186-440): 4.25e-48: 173: 15.56		TCPA_HUMAN (10-533): 0: 549: 33.09
+	Hs
		573406 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		TCPA_HUMAN (10-533): 0: 549: 33.09
+	Hs
		821355 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		TCPE_HUMAN (4-530): 0: 559: 32.52
+	Hs
		573412 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		TCPA_HUMAN (10-533): 0: 549: 33.09
+	Hs
		573346 WDR5B_HUMAN (279-439): 2.9e-21: 96.1: 12.27		TCPA_HUMAN (10-533): 0: 549: 33.09
+	Mm
		945955 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		TCPD_MOUSE (16-524): 4.42e-90: 288: 34.37
+	Hs
		843289 POC1A_HUMAN (177-440): 1.72e-50: 177: 14.29		TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56
+	Hs
		843299 POC1B_HUMAN (186-440): 4.25e-48: 173: 15.56		TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56