HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.975

The method score is based on:

Property Details
Experiments 26496610, 27705803, 24981860, 12435631, 15385962, 33961781, 15225548, 35271311, 21078963
Identification Methods affinity chromatography technology, biochemical, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CAF1C_H4-bd~WD40, WD40~WD40
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0031491 - nucleosome binding
and 2 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 441
Hs

1 425
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+ Dm
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+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024