HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: T22D1 (Q15714)
TSC22 domain family protein 1 (Cerebral protein 2) (HUCEP-2) (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein)
Gene: TSC22D1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 Hs			1 1073
+	Mm
		57194 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		CHD7_MOUSE (196-716): 3.14e-14: 80.1: 9.69
+	Mm
		1157643 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		IF4G1_MOUSE (516-1073): 1.33e-10: 67.9: 12.37
+	Hs
		267882 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		SON_HUMAN (486-849): 3.79e-10: 66.5: 16.71
+	Mm
		88464 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		D3Z656_MOUSE (296-760): 1.24e-09: 64.8: 12.47
+	Hs
		245651 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15
+	Hs
		1318191 TBL1R_HUMAN (4-335): 2.6e-56: 195: 11.40		T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15
+	Hs
		1281391 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		PRR36_HUMAN (9-1025): 1.05e-28: 127: 10.13
+	Hs
		1281504 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15
+	Dm
		51528 TAF5_DROME (85-367): 9.54e-17: 84.8: 17.48		A1Z6M0_DROME (192-991): 3.85e-21: 102: 14.55
+	Hs
		152678 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		KMT2D_HUMAN (25-798): 6.74e-09: 62.7: 13.60
+	Dm
		1370339 FBXW7_DROME (224-441): 2.22e-25: 111: 15.53		Q9VLS7_DROME (1-689): 2.91e-10: 67: 9.43
+	Hs
		577684 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		SON_HUMAN (486-849): 3.79e-10: 66.5: 16.71
+	Hs
		1153497 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		ADNP2_HUMAN (653-1067): 2.23e-09: 63.7: 13.00
+	Hs
		152663 WDR5B_HUMAN (279-439): 2.9e-21: 96.1: 12.27		KMT2D_HUMAN (25-798): 6.74e-09: 62.7: 13.60
+	Hs
		577699 NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09		SON_HUMAN (486-849): 3.79e-10: 66.5: 16.71
+	Hs
		903374 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		KMT2C_HUMAN (475-1071): 1.01e-09: 65.4: 8.46
+	Mm
		903669 WDR5_MOUSE (335-440): 3.22e-14: 75.3: 15.09		KMT2C_MOUSE (291-1072): 3.73e-09: 63.5: 9.47
+	Hs
		152622 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		KMT2D_HUMAN (25-798): 6.74e-09: 62.7: 13.60
+	Hs
		577703 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		SON_HUMAN (486-849): 3.79e-10: 66.5: 16.71
+	Hs
		903405 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		CBP_HUMAN (362-900): 7.28e-09: 62.4: 12.04