HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 26186194, 28514442, 27705803, 33961781, 26496610, 24981860, 12435631
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CAF1C_H4-bd~WD40, WD40~WD40
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0031491 - nucleosome binding
and 2 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 441
Hs

1 425
+ Mm
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs
+ Sc
+ Dm
+ Dm
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024