HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 Hs			1 551
+	Mm
		1156795 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		CPSF6_MOUSE (1-520): 4.58e-92: 294: 99.62
+	Hs
		267961 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93
+	Hs
		268177 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82
+	Hs
		267962 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Mm
		1113151 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		SC31A_MOUSE (145-488): 9.74e-27: 117: 15.44
+	Mm
		665768 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		PABP1_MOUSE (81-518): 3.65e-24: 108: 16.63
+	Hs
		1084565 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00
+	Hs
		903259 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00
+	Mm
		1111959 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		SMCA4_MOUSE (172-423): 2.26e-10: 65.7: 12.30
+	Mm
		1208064 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		DIDO1_MOUSE (151-446): 1.18e-09: 63.3: 17.16
+	Hs
		268254 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		DIDO1_HUMAN (164-416): 4.81e-09: 61.5: 21.59
+	Hs
		847050 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		1235769 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82
+	Hs
		847053 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		903367 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82
+	Hs
		903196 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Hs
		302275 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		SC31A_HUMAN (127-488): 4.72e-28: 121: 14.25
+	Hs
		516438 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		516733 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		1281353 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		DIDO1_HUMAN (164-416): 4.81e-09: 61.5: 21.59