HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: SRRM1 (Q8IYB3)
Serine/arginine repetitive matrix protein 1 (SR-related nuclear matrix protein of 160 kDa) (SRm160) (Ser/Arg-related nuclear matrix protein)
Gene: SRRM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 Hs			1 904
+	Mm
		57194 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		CHD7_MOUSE (140-840): 2.19e-33: 142: 11.54
+	Hs
		1222816 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		SRRM1_HUMAN (1-904): 7.55e-73: 259: 100.00
+	Hs
		268089 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		MDC1_HUMAN (204-903): 7.29e-13: 75: 9.61
+	Hs
		1222821 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		SRRM1_HUMAN (1-904): 7.55e-73: 259: 100.00
+	Mm
		88464 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		D3Z656_MOUSE (487-904): 3.49e-11: 69.6: 12.35
+	Hs
		268143 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		NIPBL_HUMAN (207-894): 1.06e-10: 68.2: 13.58
+	Hs
		268335 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		SRRM2_HUMAN (189-896): 4.93e-09: 62.6: 13.28
+	Hs
		1222858 NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09		SRRM1_HUMAN (1-904): 7.55e-73: 259: 100.00
+	Hs
		1108857 POC1A_HUMAN (177-440): 1.72e-50: 177: 14.29		MA7D1_HUMAN (112-867): 3.1e-27: 121: 9.91
+	Hs
		1108866 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		MA7D1_HUMAN (112-867): 3.1e-27: 121: 9.91
+	Hs
		1281391 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		PRR36_HUMAN (335-904): 6.39e-16: 85: 10.73
+	Hs
		1281511 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		C170B_HUMAN (129-899): 3.7e-09: 63: 10.66
+	Hs
		152678 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		KMT2D_HUMAN (365-903): 9.97e-09: 61.9: 12.32
+	Hs
		1056932 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		MDC1_HUMAN (204-903): 7.29e-13: 75: 9.61
+	Hs
		1288394 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		SRRM2_HUMAN (189-896): 4.93e-09: 62.6: 13.28
+	Hs
		152663 WDR5B_HUMAN (279-439): 2.9e-21: 96.1: 12.27		KMT2D_HUMAN (365-903): 9.97e-09: 61.9: 12.32
+	Hs
		1346970 NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09		SRRM2_HUMAN (189-896): 4.93e-09: 62.6: 13.28
+	Hs
		793042 LIS1_HUMAN (332-438): 2.37e-14: 76.5: 18.69		SRRM2_HUMAN (189-896): 4.93e-09: 62.6: 13.28
+	Mm
		903669 WDR5_MOUSE (335-440): 3.22e-14: 75.3: 15.09		KMT2C_MOUSE (113-814): 3.96e-09: 63: 10.86
+	Hs
		152622 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		KMT2D_HUMAN (365-903): 9.97e-09: 61.9: 12.32