Interactor 1: SF3B1 (O75533)
Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155)
Gene: SF3B1

Interactor 2: TOP1 (P11387)
DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I)
Gene: TOP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.602

The method score is based on:

Property Details
Experiments 15848144, 12549820
Identification Methods affinity chromatography technology, unspecified method, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006338 - chromatin remodeling
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1304
Hs

1 765
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024