HitPredict

Interactor 1: SF3B1 (O75533)
Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155)
Gene: SF3B1

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1304 Hs			1 245
+	Hs
		268651 SF3B1_HUMAN (1-1304): 0: 1351: 100.00		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		268647 SF3B1_HUMAN (1-1304): 0: 1351: 100.00		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Mm
		926823 2AAA_MOUSE (496-1043): 1.78e-28: 124: 14.24		1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59
+	Hs
		927364 GCN1_HUMAN (484-1290): 6.88e-28: 125: 15.65		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		647159 GCN1_HUMAN (484-1290): 6.88e-28: 125: 15.65		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		672007 2AAA_HUMAN (496-1043): 1.11e-28: 125: 14.24		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		297824 K0754_HUMAN (2-340): 5.65e-23: 109: 12.64		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		297821 K0754_HUMAN (2-340): 5.65e-23: 109: 12.64		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		297815 K0754_HUMAN (2-340): 5.65e-23: 109: 12.64		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		672068 2AAA_HUMAN (496-1043): 1.11e-28: 125: 14.24		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59