HitPredict

Interactor 1: SF3B1 (O75533)
Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155)
Gene: SF3B1

Interactor 2: SKI8 (Q9GZS3)
Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]
Gene: SKIC8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1304 Hs			1 305
+	Hs
		268811 SF3B1_HUMAN (1-1304): 0: 1351: 100.00		FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30
+	Hs
		268815 SF3B1_HUMAN (1-1304): 0: 1351: 100.00		SNR40_HUMAN (2-216): 4.5e-59: 194: 22.42
+	Hs
		209364 SF3B1_HUMAN (1-1304): 0: 1351: 100.00		PLRG1_HUMAN (4-217): 2.47e-43: 156: 22.52
+	Hs
		268646 SF3B1_HUMAN (1-1304): 0: 1351: 100.00		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		196925 SF3B1_HUMAN (1-1304): 0: 1351: 100.00		PRP4_HUMAN (218-304): 3.86e-14: 74.2: 13.68
+	Hs
		1268215 GCN1_HUMAN (484-1290): 6.88e-28: 125: 15.65		FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30
+	Hs
		672231 2AAA_HUMAN (496-1043): 1.11e-28: 125: 14.24		FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30
+	Hs
		903400 GCN1_HUMAN (484-1290): 6.88e-28: 125: 15.65		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33