HitPredict

Interactor 1: DAB1 (O75553)
Disabled homolog 1
Gene: DAB1

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	18076569, 23178720, 23506116
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 588 Hs			1 665
+	Hs
		957207 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Mm
		957150 DAB2_MOUSE (8-587): 1.14e-43: 168: 23.51		SH3K1_MOUSE (1-665): 4.53e-118: 370: 87.59
+	Hs
		1191815 ANS1B_HUMAN (9-229): 2.08e-44: 171: 17.70		CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22
+	Hs
		269120 DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Mm
		956235 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		NCK1_MOUSE (104-421): 1.23e-32: 131: 15.93
+	Hs
		269148 DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00		ITSN1_HUMAN (68-454): 2.48e-21: 101: 14.01
+	Hs
		208964 DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00		NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77
+	Mm
		223010 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		NCK2_MOUSE (184-428): 6.56e-15: 78.9: 12.41
+	Mm
		957139 DAB2_MOUSE (8-587): 1.14e-43: 168: 23.51		GRB2_MOUSE (2-158): 6.83e-33: 128: 19.91
+	Hs
		557659 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		924477 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Ce
		1353620 NUMB1_CAEEL (28-294): 6.55e-51: 186: 19.34		Q9U2T9_CAEEL (142-349): 4.59e-14: 78.1: 18.48
+	Mm
		957157 DAB2_MOUSE (8-587): 1.14e-43: 168: 23.51		ITSN1_MOUSE (120-519): 1.9e-19: 95.5: 14.11
+	Hs
		957186 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		ITSN1_HUMAN (68-454): 2.48e-21: 101: 14.01
+	Mm
		1206702 ANS1B_MOUSE (9-236): 2.44e-42: 165: 15.95		ITSN1_MOUSE (120-519): 1.9e-19: 95.5: 14.11
+	Hs
		209098 ANS1B_HUMAN (9-229): 2.08e-44: 171: 17.70		NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77
+	Mm
		1206687 ANS1B_MOUSE (9-236): 2.44e-42: 165: 15.95		ARHG7_MOUSE (228-354): 2.05e-13: 75.9: 21.88
+	Hs
		235513 Q49AR9_HUMAN (11-306): 1.73e-40: 157: 16.67		VINEX_HUMAN (67-445): 2.37e-15: 81.7: 19.82
+	Mm
		957144 DAB2_MOUSE (8-587): 1.14e-43: 168: 23.51		NOSTN_MOUSE (240-335): 1.6e-09: 62.8: 39.58
+	Rn
		192744 SYNJ1_RAT (96-587): 2.76e-40: 159: 14.72		SRBS2_RAT (3-155): 3.11e-11: 68.9: 30.25