Interactor 1: WBP4 (O75554)
WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21) (WW domain-containing-binding protein 4)
Gene: WBP4

Interactor 2: U520 (O75643)
U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)
Gene: SNRNP200

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.655

The method score is based on:

Property Details
Experiments 28838205, 35241646
Identification Methods two hybrid, pull down, x-ray crystallography, two hybrid array, cross-linking study, nuclear magnetic resonance, isothermal titration calorimetry, filter binding, molecular sieving
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0071005 - U2-type precatalytic spliceosome
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 376
Hs

1 2136
+ Hs
+ At
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+ Sp
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024