HitPredict

Interactor 1: WBP4 (O75554)
WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21) (WW domain-containing-binding protein 4)
Gene: WBP4

Interactor 2: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	16055720
Identification Methods	pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 376 Hs			1 551
+	Hs
		269254 WBP4_HUMAN (1-376): 3.94e-99: 300: 100.00		CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82
+	Hs
		263650 PR40A_HUMAN (98-260): 1.44e-31: 128: 21.47		CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00
+	Hs
		269201 WBP4_HUMAN (1-376): 3.94e-99: 300: 100.00		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		125492 WWP2_HUMAN (21-243): 7.51e-12: 69: 13.90		CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00
+	Hs
		263733 PR40A_HUMAN (98-260): 1.44e-31: 128: 21.47		CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82
+	Hs
		125259 WWP2_HUMAN (21-243): 7.51e-12: 69: 13.90		SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93
+	Hs
		125581 WWP2_HUMAN (21-243): 7.51e-12: 69: 13.90		CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82
+	Hs
		125260 WWP2_HUMAN (21-243): 7.51e-12: 69: 13.90		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		125430 WWP2_HUMAN (21-243): 7.51e-12: 69: 13.90		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Sc
		376704 PRP40_YEAST (126-271): 6.69e-26: 110: 21.92		PABP_YEAST (82-174): 3.01e-12: 71.1: 27.96
+	Hs
		125122 WWP2_HUMAN (21-243): 7.51e-12: 69: 13.90		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		125274 WWP2_HUMAN (21-243): 7.51e-12: 69: 13.90		SC24C_HUMAN (233-440): 1.79e-12: 72.2: 17.05
+	Hs
		125061 WWP2_HUMAN (21-243): 7.51e-12: 69: 13.90		SC24D_HUMAN (131-353): 2.02e-11: 68.8: 21.49
+	Mm
		1208066 WWP2_MOUSE (43-243): 4.32e-12: 69.7: 14.90		DIDO1_MOUSE (151-446): 1.18e-09: 63.3: 17.16
+	Hs
		125687 WWP2_HUMAN (21-243): 7.51e-12: 69: 13.90		DIDO1_HUMAN (164-416): 4.81e-09: 61.5: 21.59
+	Hs
		125698 WWP2_HUMAN (21-243): 7.51e-12: 69: 13.90		WDR33_HUMAN (180-396): 5.21e-09: 61.5: 24.69