HitPredict

Interactor 1: PRKRA (O75569)
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PKR-associated protein X) (PKR-associating protein X) (Protein activator of the interferon-induced protein kinase) (Protein kinase, interferon-inducible double-stranded RNA-dependent activator)
Gene: PRKRA

Interactor 2: TRBP2 (Q15633)
RISC-loading complex subunit TARBP2 (TAR RNA-binding protein 2) (Trans-activation-responsive RNA-binding protein)
Gene: TARBP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 25910212, 33961781, 29231267, 21900206, 24778252, 25416956, 32296183, unassigned1304, 16424907
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid bait and prey pooling approach, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains dsrm~dsrm
Common GO terms GO:0003725 - double-stranded RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 12 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 313
Hs

1 366
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024