HitPredict

Interactor 1: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6

Interactor 2: CAV1 (Q03135)
Caveolin-1
Gene: CAV1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.650

The method score is based on:

Property Details
Experiments 28966723, 16890161, 34079125
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005102 - signaling receptor binding
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0031410 - cytoplasmic vesicle
GO:0031901 - early endosome membrane
and 2 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1613
Hs

1 178
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024