HitPredict

Interactor 1: MYCB2 (O75592)
E3 ubiquitin-protein ligase MYCBP2 (EC 2.3.2.33) (Myc-binding protein 2) (Protein associated with Myc)
Gene: MYCBP2

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.689

Property	Details
Experiments	35271311, 36931259, 23444366, 15161933
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4678 Hs			1 245
+	Hs
		270608 MYCB2_HUMAN (1-4678): 0: 6870: 100.00		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		270610 MYCB2_HUMAN (1-4678): 0: 6870: 100.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		270581 MYCB2_HUMAN (1-4678): 0: 6870: 100.00		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		270582 MYCB2_HUMAN (1-4678): 0: 6870: 100.00		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		270618 MYCB2_HUMAN (1-4678): 0: 6870: 100.00		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		270607 MYCB2_HUMAN (1-4678): 0: 6870: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Mm
		926825 MYCB2_MOUSE (1-4678): 0: 6709: 95.44		1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00
+	Hs
		101681 F8VWT9_HUMAN (202-472): 8.41e-67: 256: 23.47		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		101690 F8VWT9_HUMAN (202-472): 8.41e-67: 256: 23.47		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		101682 F8VWT9_HUMAN (202-472): 8.41e-67: 256: 23.47		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Mm
		926792 HERC2_MOUSE (704-1143): 4.88e-42: 174: 12.96		1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00
+	Hs
		101693 F8VWT9_HUMAN (202-472): 8.41e-67: 256: 23.47		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		101685 F8VWT9_HUMAN (202-472): 8.41e-67: 256: 23.47		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		909933 ALS2_HUMAN (229-655): 1.31e-25: 119: 12.11		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		647204 ALS2_HUMAN (229-655): 1.31e-25: 119: 12.11		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927426 ALS2_HUMAN (229-655): 1.31e-25: 119: 12.11		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683641 ALS2_HUMAN (229-655): 1.31e-25: 119: 12.11		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Mm
		935551 RCC2_MOUSE (304-656): 1.04e-27: 123: 13.89		1433F_MOUSE (2-242): 4.62e-106: 308: 71.43
+	Hs
		982404 ALS2_HUMAN (229-655): 1.31e-25: 119: 12.11		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		905011 ALS2_HUMAN (229-655): 1.31e-25: 119: 12.11		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33