HitPredict

Interactor 1: UBP2 (O75604)
Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2)
Gene: USP2

Interactor 2: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	24623722
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0007517 - muscle organ development GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 605 Hs			1 664
+	Hs
		271076 UBP2_HUMAN (1-605): 0: 636: 100.00		LMNB2_HUMAN (21-580): 7.45e-51: 188: 52.68
+	Hs
		271159 UBP2_HUMAN (1-605): 0: 636: 100.00		KRT35_HUMAN (30-387): 1.7e-41: 158: 24.58
+	Hs
		280779 UBP8_HUMAN (61-602): 1.91e-124: 395: 28.81		KRT36_HUMAN (31-457): 9.65e-119: 364: 23.83
+	Hs
		271020 UBP2_HUMAN (1-605): 0: 636: 100.00		NFL_HUMAN (28-433): 1.96e-26: 115: 27.07
+	Hs
		777030 UBP8_HUMAN (61-602): 1.91e-124: 395: 28.81		KRT85_HUMAN (25-387): 4.71e-48: 178: 24.93
+	Hs
		595455 UBP36_HUMAN (162-598): 2.8e-102: 336: 27.15		LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37
+	Hs
		595227 UBP10_HUMAN (94-600): 1.5e-102: 330: 18.96		LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37
+	Hs
		86494 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		C4AM86_HUMAN (30-394): 2.18e-115: 354: 25.68
+	Hs
		535396 UBP10_HUMAN (94-600): 1.5e-102: 330: 18.96		GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43
+	Hs
		1345488 UBP36_HUMAN (162-598): 2.8e-102: 336: 27.15		KRT84_HUMAN (233-645): 2.05e-11: 69.1: 13.60
+	Hs
		360574 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		595154 UBP11_HUMAN (453-605): 5.32e-29: 124: 37.98		LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37
+	Hs
		943707 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		KRT85_HUMAN (25-387): 4.71e-48: 178: 24.93
+	Hs
		1270318 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		KRT35_HUMAN (30-387): 1.7e-41: 158: 24.58
+	Hs
		443408 UBP11_HUMAN (453-605): 5.32e-29: 124: 37.98		VIME_HUMAN (27-389): 3.94e-31: 129: 28.93
+	Hs
		443899 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		VIME_HUMAN (27-389): 3.94e-31: 129: 28.93
+	Hs
		569063 UBP11_HUMAN (453-605): 5.32e-29: 124: 37.98		DESM_HUMAN (27-389): 6.1e-28: 119: 30.03
+	Hs
		1055226 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		KRT81_HUMAN (250-556): 3.72e-10: 64.8: 12.93