HitPredict

Interactor 1: UBP2 (O75604)
Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2)
Gene: USP2

Interactor 2: AAPK1 (Q13131)
5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)
Gene: PRKAA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16306228
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0046872 - metal ion binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 605 Hs			1 559
+	Hs
		1025134 UBP10_HUMAN (94-600): 1.5e-102: 330: 18.96		AAPK1_HUMAN (1-559): 0: 595: 100.00
+	Hs
		871383 UBP10_HUMAN (94-600): 1.5e-102: 330: 18.96		AAPK2_HUMAN (13-559): 0: 535: 75.41
+	Hs
		1183143 UBP21_HUMAN (72-604): 7.31e-131: 396: 33.86		MARK2_HUMAN (10-545): 5.04e-150: 451: 29.64
+	Hs
		647975 UBP21_HUMAN (72-604): 7.31e-131: 396: 33.86		MARK3_HUMAN (3-543): 7.31e-144: 434: 28.21
+	Hs
		1296789 UBP21_HUMAN (72-604): 7.31e-131: 396: 33.86		MARK4_HUMAN (18-543): 9.01e-140: 424: 28.76
+	Hs
		1183139 UBP36_HUMAN (162-598): 2.8e-102: 336: 27.15		MARK2_HUMAN (10-545): 5.04e-150: 451: 29.64
+	Sc
		419924 UBP8_YEAST (265-600): 5.25e-95: 301: 27.86		SNF1_YEAST (23-475): 3.4e-141: 424: 38.62