HitPredict

Interactor 1: UBP2 (O75604)
Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2)
Gene: USP2

Interactor 2: H2A2C (Q16777)
Histone H2A type 2-C (H2A-clustered histone 20) (Histone H2A-GL101) (Histone H2A/q)
Gene: H2AC20

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	26507658
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 605 Hs			1 129
+	Hs
		271018 UBP2_HUMAN (1-605): 0: 636: 100.00		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		777047 UBP8_HUMAN (61-602): 1.91e-124: 395: 28.81		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		1151394 UBP21_HUMAN (72-604): 7.31e-131: 396: 33.86		H2A2A_HUMAN (1-127): 3.37e-65: 195: 97.64
+	Hs
		1087135 UBP22_HUMAN (232-599): 1.07e-113: 351: 30.12		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		391971 UBP22_HUMAN (232-599): 1.07e-113: 351: 30.12		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		555508 U17L2_HUMAN (193-604): 2.62e-112: 347: 26.08		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12
+	Hs
		1312240 UBP36_HUMAN (162-598): 2.8e-102: 336: 27.15		H2AJ_HUMAN (1-129): 1.81e-66: 198: 96.90
+	Hs
		1087027 UBP51_HUMAN (236-599): 9.24e-105: 333: 26.75		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		905382 UBP46_HUMAN (243-600): 1.24e-108: 332: 24.33		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		391943 UBP36_HUMAN (162-598): 2.8e-102: 336: 27.15		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		1058217 UBP10_HUMAN (94-600): 1.5e-102: 330: 18.96		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		259285 UBP12_HUMAN (266-600): 3.85e-107: 329: 26.50		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		391756 UBP51_HUMAN (236-599): 9.24e-105: 333: 26.75		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		391991 UBP3_HUMAN (231-602): 1.99e-106: 332: 32.83		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Sc
		392501 UBP8_YEAST (265-600): 5.25e-95: 301: 27.86		H2A2_YEAST (16-129): 1.63e-52: 163: 78.95
+	Hs
		1087144 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		555362 UBP11_HUMAN (453-605): 5.32e-29: 124: 37.98		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12