HitPredict

Interactor 1: UBP2 (O75604)
Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2)
Gene: USP2

Interactor 2: RN125 (Q96EQ8)
E3 ubiquitin-protein ligase RNF125 (EC 2.3.2.27) (RING finger protein 125) (T-cell RING activation protein 1) (TRAC-1)
Gene: RNF125

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	23105109
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 605 Hs			1 232
+	Hs
		271032 UBP2_HUMAN (1-605): 0: 636: 100.00		RO52_HUMAN (22-227): 1.26e-41: 149: 13.30
+	Hs
		271163 UBP2_HUMAN (1-605): 0: 636: 100.00		RN166_HUMAN (1-224): 1.46e-42: 145: 30.83
+	Hs
		271195 UBP2_HUMAN (1-605): 0: 636: 100.00		TRI39_HUMAN (28-229): 3.66e-38: 140: 16.90
+	Hs
		271189 UBP2_HUMAN (1-605): 0: 636: 100.00		TRIM5_HUMAN (24-229): 2.94e-33: 126: 15.81
+	Hs
		271027 UBP2_HUMAN (1-605): 0: 636: 100.00		TRI27_HUMAN (22-228): 7.77e-33: 125: 15.49
+	Hs
		271221 UBP2_HUMAN (1-605): 0: 636: 100.00		TRI35_HUMAN (18-229): 2.74e-32: 124: 12.67
+	Hs
		271142 UBP2_HUMAN (1-605): 0: 636: 100.00		LNX2_HUMAN (1-138): 3.55e-26: 108: 22.82
+	Hs
		271184 UBP2_HUMAN (1-605): 0: 636: 100.00		TRI34_HUMAN (31-167): 2.14e-26: 108: 20.14
+	Hs
		271228 UBP2_HUMAN (1-605): 0: 636: 100.00		TRAF6_HUMAN (6-175): 2.58e-26: 108: 21.39
+	Hs
		271105 UBP2_HUMAN (1-605): 0: 636: 100.00		LONF1_HUMAN (32-81): 1.24e-10: 62.4: 36.00
+	Hs
		1318717 UBP21_HUMAN (72-604): 7.31e-131: 396: 33.86		TRIM5_HUMAN (24-229): 2.94e-33: 126: 15.81
+	Hs
		1356323 UBP21_HUMAN (72-604): 7.31e-131: 396: 33.86		TRAF6_HUMAN (6-175): 2.58e-26: 108: 21.39
+	Hs
		1019375 UBP36_HUMAN (162-598): 2.8e-102: 336: 27.15		TRI26_HUMAN (22-228): 2.25e-46: 163: 14.88
+	Hs
		1019313 UBP39_HUMAN (57-600): 3.42e-104: 327: 19.75		TRI26_HUMAN (22-228): 2.25e-46: 163: 14.88
+	Hs
		1024693 U17L2_HUMAN (193-604): 2.62e-112: 347: 26.08		TRAF3_HUMAN (5-175): 4.42e-33: 127: 19.89
+	Hs
		1058275 UBP10_HUMAN (94-600): 1.5e-102: 330: 18.96		TRI11_HUMAN (22-215): 2.41e-33: 126: 15.50
+	Hs
		777079 UBP8_HUMAN (61-602): 1.91e-124: 395: 28.81		RNF41_HUMAN (37-120): 3.22e-10: 60.9: 24.18
+	Mm
		1193545 UBP8_MOUSE (169-602): 1.41e-122: 389: 34.10		RNF41_MOUSE (37-120): 3.51e-10: 60.5: 24.18
+	Hs
		1377879 UBP3_HUMAN (231-602): 1.99e-106: 332: 32.83		TRAF6_HUMAN (6-175): 2.58e-26: 108: 21.39
+	Hs
		1058328 UBP10_HUMAN (94-600): 1.5e-102: 330: 18.96		TRAF6_HUMAN (6-175): 2.58e-26: 108: 21.39