HitPredict

Interactor 1: UBP2 (O75604)
Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2)
Gene: USP2

Interactor 2: HOIL1 (Q9BYM8)
RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 2.3.2.31) (HBV-associated factor 4) (Heme-oxidized IRP2 ubiquitin ligase 1) (HOIL-1) (Hepatitis B virus X-associated protein 4) (RING finger protein 54) (RING-type E3 ubiquitin transferase HOIL-1) (Ubiquitin-conjugating enzyme 7-interacting protein 3)
Gene: RBCK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	23105109
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 605 Hs			1 510
+	Hs
		1317098 UBP21_HUMAN (72-604): 7.31e-131: 396: 33.86		HOIL1_HUMAN (1-510): 0: 577: 100.00
+	Hs
		226067 UBP2_HUMAN (1-605): 0: 636: 100.00		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80
+	Hs
		271126 UBP2_HUMAN (1-605): 0: 636: 100.00		R144B_HUMAN (276-477): 1.67e-54: 187: 20.57
+	Hs
		1317102 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		HOIL1_HUMAN (1-510): 0: 577: 100.00
+	Hs
		1244176 UBP32_HUMAN (540-597): 1.12e-09: 63.9: 46.55		HOIL1_HUMAN (1-510): 0: 577: 100.00
+	Hs
		226736 UBP8_HUMAN (61-602): 1.91e-124: 395: 28.81		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80
+	Hs
		1121221 UBP39_HUMAN (57-600): 3.42e-104: 327: 19.75		ARI1_HUMAN (216-496): 1.87e-68: 231: 18.09
+	Hs
		1168542 UBP22_HUMAN (232-599): 1.07e-113: 351: 30.12		RN19B_HUMAN (277-477): 1.57e-57: 205: 22.97
+	Hs
		905386 UBP46_HUMAN (243-600): 1.24e-108: 332: 24.33		RN19B_HUMAN (277-477): 1.57e-57: 205: 22.97
+	Hs
		259291 UBP12_HUMAN (266-600): 3.85e-107: 329: 26.50		RN19B_HUMAN (277-477): 1.57e-57: 205: 22.97
+	Hs
		227466 UBP10_HUMAN (94-600): 1.5e-102: 330: 18.96		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80
+	Hs
		227649 UBP39_HUMAN (57-600): 3.42e-104: 327: 19.75		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80
+	Hs
		842149 UBP21_HUMAN (72-604): 7.31e-131: 396: 33.86		R144A_HUMAN (279-476): 3.85e-28: 115: 20.98
+	Hs
		1168544 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		RN19B_HUMAN (277-477): 1.57e-57: 205: 22.97
+	Hs
		1024362 UBP4_HUMAN (447-597): 2.22e-28: 122: 42.76		RN19B_HUMAN (277-477): 1.57e-57: 205: 22.97
+	Hs
		229159 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80
+	Hs
		1190005 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		R144B_HUMAN (276-477): 1.67e-54: 187: 20.57
+	Hs
		842134 UBP32_HUMAN (540-597): 1.12e-09: 63.9: 46.55		R144A_HUMAN (279-476): 3.85e-28: 115: 20.98