HitPredict

Interactor 1: UBP2 (O75604)
Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2)
Gene: USP2

Interactor 2: TRIM8 (Q9BZR9)
E3 ubiquitin-protein ligase TRIM8 (EC 2.3.2.27) (Glioblastoma-expressed RING finger protein) (RING finger protein 27) (RING-type E3 ubiquitin transferase TRIM8) (Tripartite motif-containing protein 8)
Gene: TRIM8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	23105109
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 605 Hs			1 551
+	Hs
		271032 UBP2_HUMAN (1-605): 0: 636: 100.00		RO52_HUMAN (1-512): 7.11e-85: 273: 13.90
+	Hs
		271195 UBP2_HUMAN (1-605): 0: 636: 100.00		TRI39_HUMAN (6-526): 1.65e-75: 250: 14.67
+	Hs
		271189 UBP2_HUMAN (1-605): 0: 636: 100.00		TRIM5_HUMAN (1-521): 1.5e-74: 246: 14.08
+	Hs
		271214 UBP2_HUMAN (1-605): 0: 636: 100.00		TRIM1_HUMAN (6-453): 2.55e-72: 246: 19.88
+	Hs
		271027 UBP2_HUMAN (1-605): 0: 636: 100.00		TRI27_HUMAN (1-531): 9.22e-71: 237: 12.63
+	Hs
		271128 UBP2_HUMAN (1-605): 0: 636: 100.00		TRI46_HUMAN (50-347): 4.73e-62: 219: 21.31
+	Hs
		271184 UBP2_HUMAN (1-605): 0: 636: 100.00		TRI34_HUMAN (1-521): 1.7e-63: 217: 13.84
+	Hs
		271162 UBP2_HUMAN (1-605): 0: 636: 100.00		TRI63_HUMAN (2-347): 1.63e-59: 202: 19.67
+	Hs
		271186 UBP2_HUMAN (1-605): 0: 636: 100.00		TRI54_HUMAN (2-347): 4.95e-59: 202: 17.76
+	Hs
		271188 UBP2_HUMAN (1-605): 0: 636: 100.00		TRIM9_HUMAN (45-397): 2.93e-56: 202: 16.30
+	Hs
		271221 UBP2_HUMAN (1-605): 0: 636: 100.00		TRI35_HUMAN (6-289): 6.71e-49: 178: 26.12
+	Hs
		1318357 UBP21_HUMAN (72-604): 7.31e-131: 396: 33.86		TRIM8_HUMAN (1-551): 4.58e-135: 405: 100.00
+	Hs
		271136 UBP2_HUMAN (1-605): 0: 636: 100.00		TRI50_HUMAN (9-252): 3.32e-13: 73.9: 23.36
+	Hs
		1318717 UBP21_HUMAN (72-604): 7.31e-131: 396: 33.86		TRIM5_HUMAN (1-521): 1.5e-74: 246: 14.08
+	Hs
		1282068 UBP21_HUMAN (72-604): 7.31e-131: 396: 33.86		TRI63_HUMAN (2-347): 1.63e-59: 202: 19.67
+	Hs
		1317484 UBP21_HUMAN (72-604): 7.31e-131: 396: 33.86		TRI54_HUMAN (2-347): 4.95e-59: 202: 17.76
+	Hs
		1318685 UBP21_HUMAN (72-604): 7.31e-131: 396: 33.86		TRIM9_HUMAN (45-397): 2.93e-56: 202: 16.30
+	Hs
		777062 UBP8_HUMAN (61-602): 1.91e-124: 395: 28.81		TRI63_HUMAN (2-347): 1.63e-59: 202: 19.67
+	Hs
		777074 UBP8_HUMAN (61-602): 1.91e-124: 395: 28.81		TRI54_HUMAN (2-347): 4.95e-59: 202: 17.76
+	Hs
		777075 UBP8_HUMAN (61-602): 1.91e-124: 395: 28.81		TRI55_HUMAN (2-347): 8.15e-53: 190: 19.18