HitPredict

Interactor 1: A0A0C4DFT8 (A0A0C4DFT8)
Jade family PHD finger 2
Gene: JADE2

Interactor 2: ING5 (Q8WYH8)
Inhibitor of growth protein 5 (p28ING5)
Gene: ING5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EPL1~ING
Common GO terms	GO:0000123 - histone acetyltransferase complex GO:0005654 - nucleoplasm GO:0046872 - metal ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 791 Hs			1 240
+	Hs
		1264487 JADE2_HUMAN (1-791): 0: 794: 99.87		ING5_HUMAN (1-240): 1.55e-98: 288: 100.00
+	Hs
		2717 A0A0C4DFT8_HUMAN (1-791): 0: 800: 100.00		ING4_HUMAN (1-239): 6.29e-88: 262: 69.48
+	Hs
		1343287 JADE2_HUMAN (1-791): 0: 794: 99.87		ING4_HUMAN (1-239): 6.29e-88: 262: 69.48
+	Hs
		1152683 JADE1_HUMAN (4-791): 0: 697: 47.55		ING5_HUMAN (1-240): 1.55e-98: 288: 100.00
+	Hs
		1152696 JADE1_HUMAN (4-791): 0: 697: 47.55		ING4_HUMAN (1-239): 6.29e-88: 262: 69.48
+	Hs
		1343284 JADE2_HUMAN (1-791): 0: 794: 99.87		ING3_HUMAN (162-239): 4.96e-36: 133: 53.85
+	Hs
		319285 BRD1_HUMAN (6-776): 0: 594: 21.70		ING5_HUMAN (1-240): 1.55e-98: 288: 100.00
+	Hs
		1264466 JADE3_HUMAN (4-768): 0: 586: 40.65		ING5_HUMAN (1-240): 1.55e-98: 288: 100.00
+	Hs
		876708 BRPF1_HUMAN (6-743): 0: 570: 20.03		ING5_HUMAN (1-240): 1.55e-98: 288: 100.00
+	Hs
		319380 BRD1_HUMAN (6-776): 0: 594: 21.70		ING4_HUMAN (1-239): 6.29e-88: 262: 69.48
+	Hs
		1268057 JADE3_HUMAN (4-768): 0: 586: 40.65		ING4_HUMAN (1-239): 6.29e-88: 262: 69.48
+	Hs
		876727 BRPF1_HUMAN (6-743): 0: 570: 20.03		ING4_HUMAN (1-239): 6.29e-88: 262: 69.48
+	Hs
		1264497 BRPF3_HUMAN (2-767): 7.25e-168: 518: 20.07		ING5_HUMAN (1-240): 1.55e-98: 288: 100.00
+	Hs
		1356827 BRPF3_HUMAN (2-767): 7.25e-168: 518: 20.07		ING4_HUMAN (1-239): 6.29e-88: 262: 69.48
+	Dm
		1177410 BRDH_DROME (22-720): 9.97e-169: 526: 24.05		ING5_DROME (1-239): 9.67e-76: 232: 46.32
+	Hs
		1268053 JADE3_HUMAN (4-768): 0: 586: 40.65		ING3_HUMAN (162-239): 4.96e-36: 133: 53.85
+	Hs
		1348038 BRPF3_HUMAN (2-767): 7.25e-168: 518: 20.07		ING3_HUMAN (162-239): 4.96e-36: 133: 53.85
+	Sc
		995740 NTO1_YEAST (72-516): 4.96e-107: 346: 24.70		YNG1_YEAST (10-240): 4.08e-47: 157: 22.94