Interactor 1: DEPD5 (O75140)
GATOR1 complex protein DEPDC5 (DEP domain-containing protein 5)
Gene: DEPDC5
Interactor 2: SAMTR (Q1RMZ1)
S-adenosylmethionine sensor upstream of mTORC1 (Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)
Gene: SAMTOR
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.73 | 0.55 | 0.634 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 33961781, unassigned3799 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005829 - cytosol GO:0034198 - cellular response to amino acid starvation GO:0044877 - protein-containing complex binding GO:1904262 - negative regulation of TORC1 signaling |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
