HitPredict

Interactor 1: SPB7 (O75635)
Serpin B7 (Megsin) (TP55)
Gene: SERPINB7

Interactor 2: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34732716
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 317
+	Hs
		397016 PAI2_HUMAN (1-380): 2.44e-164: 468: 33.98		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818577 SPB13_HUMAN (1-380): 2.3e-156: 446: 37.50		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		817802 SPB8_HUMAN (1-380): 2.22e-155: 443: 36.10		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		675627 ILEU_HUMAN (1-380): 8.43e-155: 442: 38.30		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		344176 A1AT_HUMAN (2-380): 2.63e-146: 422: 26.96		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818366 SPB12_HUMAN (1-380): 9.19e-146: 420: 38.77		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		344108 ANT3_HUMAN (4-380): 6.88e-142: 413: 32.56		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		738732 SPB5_HUMAN (1-380): 1.88e-134: 390: 31.36		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		397097 PAI1_HUMAN (4-380): 6.81e-133: 387: 26.94		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818224 SPA12_HUMAN (4-380): 4.77e-132: 386: 27.11		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		668017 SPB3_HUMAN (1-380): 6.18e-151: 433: 39.80		CIC_HUMAN (3-272): 8.9e-33: 130: 22.26
+	Hs
		331682 AACT_HUMAN (4-380): 1.07e-146: 423: 31.07		NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71
+	Hs
		331681 A1AT_HUMAN (2-380): 2.63e-146: 422: 26.96		NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71