HitPredict

Interactor 1: U520 (O75643)
U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)
Gene: SNRNP200

Interactor 2: CD2B2 (O95400)
CD2 antigen cytoplasmic tail-binding protein 2 (CD2 cytoplasmic domain-binding protein 2) (CD2 tail-binding protein 2) (U5 snRNP 52K protein) (U5-52K)
Gene: CD2BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.735

Property	Details
Experiments	28514442, 27173435, 28561026, 17353931, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005682 - U5 snRNP
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2136 Hs			1 341
+	Sc
		697208 BRR2_YEAST (4-2127): 0: 1258: 38.75		LIN1_YEAST (16-326): 1.54e-62: 204: 21.84
+	Hs
		313220 DDX5_HUMAN (1241-1718): 1.86e-108: 362: 12.47		CD2B2_HUMAN (1-341): 8.95e-134: 386: 100.00
+	Hs
		313311 DDX42_HUMAN (231-900): 2.59e-103: 357: 13.42		CD2B2_HUMAN (1-341): 8.95e-134: 386: 100.00
+	Hs
		313347 DDX23_HUMAN (1241-1748): 1.71e-87: 307: 14.36		CD2B2_HUMAN (1-341): 8.95e-134: 386: 100.00
+	Hs
		313278 DHX8_HUMAN (1313-1903): 1.71e-65: 247: 11.81		CD2B2_HUMAN (1-341): 8.95e-134: 386: 100.00
+	Hs
		313327 PRP16_HUMAN (1317-1920): 4.33e-65: 246: 11.76		CD2B2_HUMAN (1-341): 8.95e-134: 386: 100.00