HitPredict

Interactor 1: U520 (O75643)
U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)
Gene: SNRNP200

Interactor 2: NCBP2 (P52298)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (Cell proliferation-inducing gene 55 protein) (NCBP 20 kDa subunit) (CBP20) (NCBP-interacting protein 1) (NIP1)
Gene: NCBP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32960270
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2136 Hs			1 156
+	Hs
		516589 ASCC3_HUMAN (56-2134): 0: 1449: 38.34		PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41
+	Sc
		697273 BRR2_YEAST (4-2127): 0: 1258: 38.75		NCBP2_YEAST (10-150): 3.97e-39: 132: 52.48
+	Sc
		697283 BRR2_YEAST (4-2127): 0: 1258: 38.75		HSH49_YEAST (37-113): 2.85e-25: 97.8: 37.18
+	Hs
		571369 DDX5_HUMAN (1241-1718): 1.86e-108: 362: 12.47		NCBP2_HUMAN (1-156): 2.27e-48: 154: 100.00
+	Hs
		853939 DDX42_HUMAN (231-900): 2.59e-103: 357: 13.42		NCBP2_HUMAN (1-156): 2.27e-48: 154: 100.00
+	Hs
		786913 MTREX_HUMAN (1287-2037): 2.62e-101: 354: 18.12		NCBP2_HUMAN (1-156): 2.27e-48: 154: 100.00
+	Sc
		624191 DBP2_YEAST (347-898): 8.71e-101: 338: 13.47		NCBP2_YEAST (10-150): 3.97e-39: 132: 52.48
+	Sc
		810941 MTR4_YEAST (1270-1848): 1.11e-94: 335: 19.41		NCBP2_YEAST (10-150): 3.97e-39: 132: 52.48
+	Hs
		571469 DDX5_HUMAN (1241-1718): 1.86e-108: 362: 12.47		ELAV1_HUMAN (7-123): 1.27e-24: 98.4: 18.49
+	Hs
		1077436 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		ELAV1_HUMAN (7-123): 1.27e-24: 98.4: 18.49
+	Mm
		857351 Q8BTS0_MOUSE (1241-1718): 2.78e-108: 362: 12.47		TIA1_MOUSE (1-140): 7e-21: 89.1: 19.58
+	Mm
		857323 DDX17_MOUSE (405-901): 7.77e-106: 356: 13.72		TIA1_MOUSE (1-140): 7e-21: 89.1: 19.58
+	Sp
		143177 YE02_SCHPO (1285-1736): 1.23e-86: 310: 21.71		NCBP2_SCHPO (17-154): 1.84e-37: 128: 57.97
+	Mm
		936480 DDX5_MOUSE (376-901): 1.69e-104: 351: 12.85		TIAR_MOUSE (1-155): 2.19e-19: 84.9: 16.46
+	Sp
		143184 YE02_SCHPO (1285-1736): 1.23e-86: 310: 21.71		YKCG_SCHPO (36-123): 2.21e-30: 115: 30.68
+	Hs
		1073596 DDX42_HUMAN (231-900): 2.59e-103: 357: 13.42		SF3B4_HUMAN (30-116): 8.18e-11: 60.8: 23.86
+	Hs
		1073611 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		SF3B4_HUMAN (30-116): 8.18e-11: 60.8: 23.86
+	Hs
		1313211 DDX23_HUMAN (1241-1748): 1.71e-87: 307: 14.36		PUF60_HUMAN (30-113): 1.88e-17: 80.1: 30.95