HitPredict

Interactor 1: U520 (O75643)
U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)
Gene: SNRNP200

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33306668
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC4_WD40~DEAD
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2136 Hs			1 496
+	Hs
		272231 U520_HUMAN (1-2136): 0: 1844: 100.00		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		272239 U520_HUMAN (1-2136): 0: 1844: 100.00		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		272085 U520_HUMAN (1-2136): 0: 1844: 100.00		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		1232187 ASCC3_HUMAN (56-2134): 0: 1449: 38.34		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		1271615 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		1271679 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		NLE1_HUMAN (52-385): 3.28e-60: 207: 16.32
+	Hs
		224809 DHX16_HUMAN (1094-2008): 1.27e-67: 252: 11.11		CD20B_HUMAN (183-473): 8.48e-94: 295: 37.16
+	Hs
		571547 DDX5_HUMAN (1241-1718): 1.86e-108: 362: 12.47		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		1271621 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		786997 MTREX_HUMAN (1287-2037): 2.62e-101: 354: 18.12		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		224824 DHX16_HUMAN (1094-2008): 1.27e-67: 252: 11.11		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		1288280 DDX23_HUMAN (1241-1748): 1.71e-87: 307: 14.36		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		571382 DDX5_HUMAN (1241-1718): 1.86e-108: 362: 12.47		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Mm
		1207270 Q8BTS0_MOUSE (1241-1718): 2.78e-108: 362: 12.47		FZR1_MOUSE (319-495): 2.95e-25: 110: 18.68
+	Hs
		571632 DDX5_HUMAN (1241-1718): 1.86e-108: 362: 12.47		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		903410 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		1271693 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Zm
		18259 A0A1D6H4I5_MAIZE (1269-2008): 1.4e-68: 257: 11.38		A0A1D6J4G2_MAIZE (260-495): 2.5e-59: 206: 20.47
+	Hs
		787034 MTREX_HUMAN (1287-2037): 2.62e-101: 354: 18.12		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		224827 DHX16_HUMAN (1094-2008): 1.27e-67: 252: 11.11		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89