HitPredict

Interactor 1: TIPRL (O75663)
TIP41-like protein (Putative MAPK-activating protein PM10) (Type 2A-interacting protein) (TIP)
Gene: TIPRL

Interactor 2: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.855

Property	Details
Experiments	23892082, 22167190, 17384681
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Metallophos~TIP41
Common GO terms	GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 309
+	Hs
		272426 TIPRL_HUMAN (1-272): 2.14e-147: 415: 100.00		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		272423 TIPRL_HUMAN (1-272): 2.14e-147: 415: 100.00		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Dm
		619937 Q9W5W6_DROME (15-254): 4.22e-109: 318: 41.25		PP2A_DROME (1-309): 0: 524: 93.85
+	Sc
		618804 TIP41_YEAST (14-254): 5.87e-92: 277: 34.34		PP2A1_YEAST (10-309): 0: 517: 76.00
+	Sc
		618867 TIP41_YEAST (14-254): 5.87e-92: 277: 34.34		PP2A2_YEAST (10-309): 0: 514: 76.67