HitPredict

Interactor 1: OFD1 (O75665)
Centriole and centriolar satellite protein OFD1 (Oral-facial-digital syndrome 1 protein) (Protein 71-7A)
Gene: OFD1

Interactor 2: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	26638075, 21988832
Identification Methods	proximity labelling technology, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005813 - centrosome GO:0005814 - centriole GO:0005829 - cytosol GO:0015630 - microtubule cytoskeleton and 1 others more... GO:0034451 - centriolar satellite
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1012 Hs			1 603
+	Hs
		861751 DCTN1_HUMAN (96-423): 6.49e-09: 62.3: 13.82		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		128951 OFD1_HUMAN (1-1012): 1.82e-122: 400: 100.00		PLK4_HUMAN (56-306): 2.18e-55: 204: 37.70
+	Hs
		682219 MYO5A_HUMAN (104-658): 3.36e-17: 89.7: 11.88		AKT2_HUMAN (18-356): 6.81e-134: 401: 26.51
+	Hs
		1071723 MRCKB_HUMAN (116-621): 1.91e-20: 100: 11.58		KS6A2_HUMAN (1-367): 4.14e-105: 335: 22.43
+	Hs
		129013 MRCKA_HUMAN (97-525): 3.54e-16: 86.2: 13.05		PLK4_HUMAN (56-306): 2.18e-55: 204: 37.70
+	Hs
		160561 DCTN1_HUMAN (96-423): 6.49e-09: 62.3: 13.82		AURKA_HUMAN (28-307): 4.39e-43: 160: 32.17