HitPredict

Interactor 1: KS6A4 (O75676)
Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)
Gene: RPS6KA4

Interactor 2: SNTB2 (Q13425)
Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)
Gene: SNTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0045202 - synapse
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 772 Hs			1 540
+	Hs
		850649 KS6A3_HUMAN (1-740): 0: 703: 41.21		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		1033875 KS6A1_HUMAN (3-739): 0: 701: 40.79		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		1046432 KS6A1_HUMAN (3-739): 0: 701: 40.79		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Hs
		1033837 KS6A1_HUMAN (3-739): 0: 701: 40.79		SNTA1_HUMAN (16-539): 1.35e-142: 422: 45.49
+	Hs
		1073488 KS6A1_HUMAN (3-739): 0: 701: 40.79		SNTG2_HUMAN (103-536): 2.07e-110: 341: 24.04
+	Hs
		117238 KS6A5_HUMAN (2-772): 0: 765: 59.38		PDLI1_HUMAN (117-417): 7.37e-46: 165: 15.02
+	Hs
		272903 KS6A4_HUMAN (1-772): 0: 787: 100.00		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		850715 KS6A3_HUMAN (1-740): 0: 703: 41.21		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		1073484 KS6A1_HUMAN (3-739): 0: 701: 40.79		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		942348 KS6A1_HUMAN (3-739): 0: 701: 40.79		DLG4_HUMAN (66-394): 4.83e-27: 117: 16.02
+	Hs
		1073495 KS6A1_HUMAN (3-739): 0: 701: 40.79		PZRN3_HUMAN (7-198): 8.64e-16: 83: 14.35
+	Hs
		1073470 KS6A1_HUMAN (3-739): 0: 701: 40.79		MAGI1_HUMAN (69-261): 1.09e-15: 82.6: 17.96
+	Hs
		568658 KAPCA_HUMAN (398-704): 1.94e-108: 336: 26.88		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Hs
		1073438 KS6A1_HUMAN (3-739): 0: 701: 40.79		PZRN4_HUMAN (55-202): 6.15e-14: 76.8: 19.08
+	Mm
		1143553 KS6A2_MOUSE (391-761): 2.16e-104: 338: 23.58		DLG4_MOUSE (66-394): 4.96e-27: 117: 16.32
+	Hs
		1071704 KS6A2_HUMAN (3-301): 4.68e-89: 297: 23.86		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		1021498 KS6A2_HUMAN (3-301): 4.68e-89: 297: 23.86		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51