HitPredict

Interactor 1: RENR (O75787)
Renin receptor (ATPase H(+)-transporting lysosomal accessory protein 2) (ATPase H(+)-transporting lysosomal-interacting protein 2) (ER-localized type I transmembrane adapter) (Embryonic liver differentiation factor 10) (N14F) (Renin/prorenin receptor) (Vacuolar ATP synthase membrane sector-associated protein M8-9) (ATP6M8-9) (V-ATPase M8.9 subunit) [Cleaved into: Renin receptor N-terminal fragment; Renin receptor C-terminal fragment]
Gene: ATP6AP2

Interactor 2: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 350 Hs			1 192
+	Hs
		274985 RENR_HUMAN (1-350): 1.38e-167: 472: 100.00		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		274917 RENR_HUMAN (1-350): 1.38e-167: 472: 100.00		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		274990 RENR_HUMAN (1-350): 1.38e-167: 472: 100.00		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		274977 RENR_HUMAN (1-350): 1.38e-167: 472: 100.00		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		274982 RENR_HUMAN (1-350): 1.38e-167: 472: 100.00		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		274903 RENR_HUMAN (1-350): 1.38e-167: 472: 100.00		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79